How_iPSC_Works_(46181969695).jpg
Summary
| Description |
Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced "dry" form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study, published January 16 in Science Translational Medicine (STM), set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment. As pictured in this illustration, researchers will take a patient's blood cells and convert them in a lab to induced Pluripotent Stem cells (iPS cells) which are capable of becoming any type of cell in the body. iPS cells would then be programmed to become retinal pigment epithelial (RPE) cells, the type of cell that dies early in the geographic atrophy form of AMD. Read more: <a href=" https://www.nih.gov/news-events/news-releases/nih-researchers-rescue-photoreceptors-prevent-blindness-animal-models-retinal-degeneration " rel="noreferrer nofollow">www.nih.gov/news-events/news-releases/nih-researchers-res...</a> Credit: National Eye Institute, NIH |
| Date | |
| Source | How iPSC Works |
| Author | NIH Image Gallery from Bethesda, Maryland, USA |
Licensing
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This image is a work of the
National Institutes of Health
, part of the
United States Department of Health and Human Services
, taken or made as part of an employee's official duties. As a
work
of the
U.S. federal government
, the image is in the
public domain
.
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This image was originally posted to Flickr by National Institutes of Health (NIH) at https://flickr.com/photos/132318516@N08/46181969695 . It was reviewed on 14 March 2020 by FlickreviewR 2 and was confirmed to be licensed under the terms of the Public Domain Mark. |