RBC_binding_site_of_PfEMP1.png
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Summary
| Description |
English:
Localisation of the RBC binding site. (A) An overall view of the Head in a space-filling representation (NTS region in mauve, DBL1α1 domain in grey, CIDR1γ domain in orange) with the docked blood group A trisaccharide (green- carbon, black - oxygen and blue - nitrogen) and heparin (carbons in yellow) molecules in stick representation. (B) Detail of the RBC-binding site with side chains whose mutations affect binding highlighted (carbons in yellow, nitrogens in blue and oxygens in red).
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| Date | |
| Source | Structural Basis for the ABO Blood-Group Dependence of Plasmodium falciparum Rosetting. PLoS Pathog 8(7): e1002781. doi:10.1371/journal.ppat.1002781 |
| Author | Vigan-Womas I, Guillotte M, Juillerat A, Hessel A, Raynal B, England P, et al. (2012) |
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