S16-1063_Ranochak,_T_MGCT-_Embryonal_+_Seminoma_+_Yolk_Sac.jpg


Summary

Description
English: Mixed Germ Cell Tumor containing embryonal carcinoma, seminoma, and yolk sac tumor. The embryonal carcinoma component (upper left, upper right, and lower left) shows pseudoglandular growth with high-grade features of large, epithelioid, anaplastic cells with prominent nucleoli, indistinct cell borders with nuclear overlapping, pleomorphism, and frequent mitoses. The seminoma component (upper center) shows large, round-polyhedral cells with distinct cell membranes, abundant clear/watery cytoplasm, large central nuclei and prominent nucleoli. The yolk sac component (lower right, hugging the embryonal component) exhibits microcystic/ reticular growth pattern.
Date
Source Own work
Author Difu Wu

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17 August 2016