S2m_structure_of_SARS-CoV.png


Summary

Description
English: Schematic representation of the SARS-CoV-1 s2m RNA secondary structure, with tertiary structural interactions indicated as long-range contacts. s2m includes GNRA-like pentaloop structure (brown), A form RNA helices (blue and purple), the three-purine asymmetric bulge (orange), and the seven-nucleotide bubble (green). Long-range tertiary contacts are indicated by thin orange and brown lines. Formation of the junction of two perpendicular helices is facilitated by a base quartet (blue) composed of two G–C pairs.
Date
Source adapted from Robertson MP, Igel H, Baertsch R, Haussler D, Ares M, Scott WG. The structure of a rigorously conserved RNA element within the SARS virus genome". PLoS Biology. 3 (1): e5. doi:10.1371/journal.pbio.0030005
Author Ting-Yu Yeh

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Captions

Schematic representation of the SARS-CoV-1 s2m RNA secondary structure, with tertiary structural interactions indicated as long range contacts. In Diamond Princess, two mutations 29736G > T and 29751G > T occurred at G13 and G28.

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20 July 2021

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