vicissitude
noun
[ vɪˈsɪsɪtjuːd ]
• a change of circumstances or fortune, typically one that is unwelcome or unpleasant.
• "her husband's sharp vicissitudes of fortune"
Similar:
change,
alteration,
alternation,
transformation,
metamorphosis,
transmutation,
mutation,
modification,
transition,
development,
shift,
switch,
turn,
reversal,
reverse,
downturn,
inconstancy,
instability,
uncertainty,
unpredictability,
chanciness,
fickleness,
variability,
changeability,
fluctuation,
vacillation,
ups and downs,
• alternation between opposite or contrasting things.
• "the vicissitude of the seasons"
Origin:
early 17th century (in the sense ‘alternation’): from French, or from Latin vicissitudo, from vicissim ‘by turns’, from vic- ‘turn, change’.