Triggering cancer cells to become normal cells – how stem cell therapies can provide new ways to stop tumors from spreading or growing back

Many tumors have cancer stem cells that help them grow and evade treatments. Differentiation therapy forces these cells to mature, stopping growth with less toxicity than traditional treatments.

Abhimanyu Thakur, Postdoctoral Scholar in Molecular Engineering, University of Chicago Pritzker School of Molecular Engineering • conversation
Jan. 11, 2023 ~7 min

Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions – and possibly grease the drug development pipeline

Successes in the lab mostly don’t translate to people. Research models that better mimic the human body could close the gap.

Chengpeng Chen, Assistant Professor of Chemistry and Biochemistry, University of Maryland, Baltimore County • conversation
Jan. 10, 2023 ~7 min


How cancer cells move and metastasize is influenced by the fluids surrounding them – understanding how tumors migrate can help stop their spread

Counterintuitively, cells move faster in thicker fluids. New research on breast cancer cells explains why, and reveals the role that fluid viscosity plays in metastasis.

Yizeng Li, Assistant Professor of Biomedical Engineering, Binghamton University, State University of New York • conversation
Jan. 9, 2023 ~7 min

Visualizing the inside of cells at previously impossible resolutions provides vivid insights into how they work

Many microscopy techniques have won Nobel Prizes over the years. Advancements like cryo-ET that allow scientists to see the individual atoms of cells can reveal their biological functions.

Jeremy Berg, Professor of Computational and Systems Biology, Associate Senior Vice Chancellor for Science Strategy and Planning, University of Pittsburgh • conversation
Jan. 6, 2023 ~7 min

Scientists discover a new way of sharing genetic information in a common ocean microbe

Prochlorococcus, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.

David L. Chandler | MIT News Office • mit
Jan. 5, 2023 ~8 min

In mouse model, scientists develop cancer vaccine that kills brain tumors

Scientists at Harvard-affiliated Brigham and Women’s Hospital have developed a cancer vaccine to simultaneously kill and prevent brain cancer in advanced mouse models.

Harvard Gazette • harvard
Jan. 4, 2023 ~4 min

Dry eye changes how injured cornea heals itself

Dry eye disease alters how the cornea heals itself after injury. Now, researchers have identified new potential therapy targets.

Jim Dryden-WUSTL • futurity
Jan. 4, 2023 ~4 min

Self-assembling proteins can store cellular “memories”

Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug.

Anne Trafton | MIT News Office • mit
Jan. 2, 2023 ~6 min


New tool can assist with identifying carbohydrate-binding proteins

Groundbreaking research can help alleviate the challenges affiliated with studying carbohydrates.

Danielle Randall Doughty | Department of Chemistry • mit
Dec. 22, 2022 ~5 min

Anti-cancer CAR-T therapy reengineers T cells to kill tumors – and researchers are expanding the limited types of cancer it can target

Immunotherapy has the potential to eliminate tumors, but works best for select patients. Engineering T cells to bypass cancer’s defenses could help expand treatment eligibility to more patients.

Gregory Allen, Assistant Professor of Medicine, University of California, San Francisco • conversation
Dec. 15, 2022 ~8 min

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