‘Fate mapping’ traces cell samples back to embryo

A computer model, quantitative fate mapping, looks back in the developmental timeline to trace the origin of cells in a fully grown organism.

Vanessa Wasta-Johns Hopkins • futurity
Dec. 15, 2022 ~6 min

Blocking this gene slows heart scarring, failure

Blocking a specific gene in people in the early stages of cardiomyopathy could halt the development of scar tissue and delay heart failure.

Federico Graciano - Duke-NUS • futurity
Dec. 9, 2022 ~6 min


Looking to retain most potent regenerative stem cells

Humans lose them after embryonic development, unlike some animals. New Harvard research offers potential insights into why.

Alice McCarthy • harvard
Dec. 8, 2022 ~4 min

Harnessing the brain's immune cells to stave off Alzheimer's and other neurodegenerative diseases

Microglia, immune cells disguised as brain cells, are known as the janitors of the brain. Dialing up their usual duties just enough could provide an avenue to treat neurodegenerative disease.

Kristine Zengeler, Ph.D. Candidate in Neuroscience, University of Virginia • conversation
Dec. 7, 2022 ~9 min

‘Dialogue’ with environment fuels cancer stem cells

New research indicates that "crosstalk" between stem cells in tumors and their environment leads to a loop that can promote cancer.

Rockefeller University • futurity
Dec. 2, 2022 ~8 min

Fewer key immune cells may contribute to Alzheimer’s

Can underproduction of key immune cells contribute to Alzheimer's? A new study suggests the answer is yes.

Andrew Smith-Rutgers • futurity
Nov. 30, 2022 ~5 min

Silent synapses are abundant in the adult brain

These immature connections may explain how the adult brain is able to form new memories and absorb new information.

Anne Trafton | MIT News Office • mit
Nov. 30, 2022 ~9 min

Scientists unveil the functional landscape of essential genes

Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.

Nicole Davis | Whitehead Institute • mit
Nov. 21, 2022 ~6 min


Why stem cell transplants for MS work so well

New research digs into why blood stem cell transplants are so effective as a therapy for multiple sclerosis.

Kurt Bodenmueller-U. Zurich • futurity
Nov. 11, 2022 ~6 min

What is inflammation? Two immunologists explain how the body responds to everything from stings to vaccination and why it sometimes goes wrong

Inflammation is a complicated and important part of how the immune system responds to threats to the body. But when the inflammatory response goes awry, it can lead to serious problems.

Mitzi Nagarkatti, Professor of Pathology, Microbiology and Immunology, University of South Carolina • conversation
Nov. 7, 2022 ~6 min

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