With programmable pixels, novel sensor improves imaging of neural activity

New camera chip design allows for optimizing each pixel’s timing to maximize signal-to-noise ratio when tracking real-time visual indicator of neural voltage.

David Orenstein | The Picower Institute for Learning and Memory • mit
June 13, 2024 ~8 min

Understanding why autism symptoms sometimes improve amid fever

With support from The Marcus Foundation, an MIT neuroscientist and a Harvard Medical School immunologist will study the “fever effect” in an effort to devise therapies that mimic its beneficial effects.

David Orenstein | The Picower Institute for Learning and Memory • mit
May 23, 2024 ~7 min


To understand cognition — and its dysfunction — neuroscientists must learn its rhythms

A new framework describes how thought arises from the coordination of neural activity driven by oscillating electric fields — a.k.a. brain “waves” or “rhythms.”

David Orenstein | The Picower Institute for Learning and Memory • mit
April 30, 2024 ~7 min

How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice

Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 7, 2024 ~8 min

A noninvasive treatment for “chemo brain”

Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.

Anne Trafton | MIT News • mit
March 6, 2024 ~7 min

Simons Center’s collaborative approach propels autism research, at MIT and beyond

Team-based targeted projects, multi-mentor fellowships ensure that scientists studying social cognition, behavior, and autism integrate multiple perspectives and approaches to pressing questions.

David Orenstein | Simons Center for the Social Brain • mit
Jan. 30, 2024 ~12 min

Evidence that gamma rhythm stimulation can treat neurological disorders is emerging

Researchers survey a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of noninvasive sensory, electrical, or magnetic stimulation of gamma brain rhythms.

David Orenstein | The Picower Institute for Learning and Memory • mit
Jan. 18, 2024 ~9 min

Study reveals a universal pattern of brain wave frequencies

Across mammalian species, brain waves are slower in deep cortical layers, while superficial layers generate faster rhythms.

Anne Trafton | MIT News • mit
Jan. 18, 2024 ~9 min


Nanoparticle-delivered RNA reduces neuroinflammation in lab tests

MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.

David Orenstein | Picower Institute • mit
Dec. 15, 2023 ~7 min

How a mutation in microglia elevates Alzheimer’s risk

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation, and contribute to Alzheimer’s pathology in other ways.

David Orenstein | The Picower Institute for Learning and Memory • mit
Dec. 4, 2023 ~7 min

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