RNA has newly identified role: Repairing serious DNA damage to maintain the genome

Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and neurodegenerative diseases.

Francesca Storici, Professor of Biological Sciences, Georgia Institute of Technology • conversation
June 16, 2025 ~6 min

Rationale engineering generates a compact new tool for gene therapy

Researchers redesign a compact RNA-guided enzyme from bacteria, making it an efficient editor of human DNA.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
May 28, 2025 ~8 min


A brief history of expansion microscopy

Since an MIT team introduced expansion microscopy in 2015, the technique has powered the science behind kidney disease, plant seeds, the microbiome, Alzheimer’s, viruses, and more.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
April 23, 2025 ~13 min

New study reveals how cleft lip and cleft palate can arise

MIT biologists have found that defects in some transfer RNA molecules can lead to the formation of these common conditions.

Anne Trafton | MIT News • mit
April 17, 2025 ~7 min

Does using e-cigarettes boost cancer risk?

"Our results contribute significantly to understanding the potential health risks of e-cigarette use..."

U. Rochester-URMC • futurity
March 3, 2025 ~6 min

An ancient RNA-guided system could simplify delivery of gene editing therapies

The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Feb. 27, 2025 ~7 min

A protein from tiny tardigrades may help cancer patients tolerate radiation therapy

When scientists stimulated cells to produce a protein that helps “water bears” survive extreme environments, the tissue showed much less DNA damage after radiation treatment.

Anne Trafton | MIT News • mit
Feb. 26, 2025 ~8 min

MIT biologists discover a new type of control over RNA splicing

They identified proteins that influence splicing of about half of all human introns, allowing for more complex types of gene regulation.

Anne Trafton | MIT News • mit
Feb. 20, 2025 ~7 min


RNA plays a surprising role in DNA repair

Researchers have discovered a surprising role for RNA in DNA repair. The work could lead to better treatments for cancer and other diseases.

Georgia Tech • futurity
Dec. 3, 2024 ~7 min

A blueprint for better cancer immunotherapies

By examining antigen architectures, MIT researchers built a therapeutic cancer vaccine that may improve tumor response to immune checkpoint blockade treatments.

Bendta Schroeder | Koch Institute • mit
Nov. 25, 2024 ~7 min

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