Regulating the regulators

Tiny microRNAs help destroy unwanted messenger RNAs in cells. New research finds how the body keeps them in check.

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genetics crispr biology rna research whitehead-institute

Silencing gene expression to cure complex diseases

Immuneering uses bioinformatics to develop new medicines while also helping large pharmaceutical companies improve their treatments.

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health medicine genetics cancer startups biology rna alzheimers data disease research drug-development school-of-engineering innovation-and-entrepreneurship-ie alumniae biological-engineering

Analyzing toehold sequences for synthetic biology

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications.

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science-technology dna synthetic-biology rna wyss-institute james-collins

Nanoparticles can turn off genes in bone marrow cells

Using these new particles, researchers could develop treatments for heart disease and other conditions.

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genetics rna research school-of-engineering nanoscience-and-nanotechnology koch-institute institute-for-medical-engineering-and-science-imes chemical-engeering

Potential drug could ‘jam’ hand, foot, and mouth disease

Targeting RNA with small molecules could pave the way for new antivirals, in particular a drug for hand, foot, and mouth disease.

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rna viruses drug-development health-and-medicine

Scientists discover new rules about “runaway” transcription

Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.

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dna physics genetics bacteria biology rna research school-of-science

The COVID-19 virus can spread through the air – here's what it'll take to detect the airborne particles

Miniaturized laboratory equipment is making it easier to identify airborne pathogens in the field, but there's still work ahead to be able to instantly determine if a room is safe or contaminated.

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dna covid-19 coronavirus pandemic rna sars-cov-2 viruses pathogens star-trek airborne-virus metagenomics next-generation-sequencing pcr

Bringing RNA into genomics

ENCODE consortium identifies RNA sequences that are involved in regulating gene expression.

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genetics biology rna research school-of-science

Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA

Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.

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neuroscience rna immunology broad-institute research cells school-of-science brain-and-cognitive-sciences computer-science-and-artificial-intelligence-laboratory-csail picower-institute huntingtons