Scientists unveil the functional landscape of essential genes

Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.

Nicole Davis | Whitehead Institute • mit
Nov. 21, 2022 ~6 min

Genome-wide screens could reveal the liver’s secrets

A new technique for studying liver cells within an organism could shed light on the genes required for regeneration.

Anne Trafton | MIT News Office • mit
Nov. 15, 2022 ~8 min


A “door” into the mitochondrial membrane

Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.

Eva Frederick | Whitehead Institute • mit
Oct. 25, 2022 ~7 min

Four from MIT receive NIH New Innovator Awards for 2022

Awards support high-risk, high-impact research from early-career investigators.

Phie Jacobs | School of Science • mit
Oct. 4, 2022 ~5 min

New CRISPR-based map ties every human gene to its function

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

Eva Frederick | Whitehead Institute • mit
June 9, 2022 ~9 min

MIT Climate and Sustainability Consortium announces recipients of inaugural MCSC Seed Awards

Twenty winning projects will link industry member priorities with research groups across campus to develop scalable climate solutions.

Molly Chase | Climate and Sustainability Consortium • mit
May 23, 2022 ~15 min

Tracing a cancer’s family tree to its roots reveals how tumors grow

Family trees of lung cancer cells reveal how cancer evolves from its earliest stages to an aggressive form capable of spreading throughout the body.

Greta Friar | Whitehead Institute • mit
May 5, 2022 ~9 min

Using plant biology to address climate change

A Climate Grand Challenges flagship project aims to reduce agriculture-driven emissions while making food crop plants heartier and more nutritious.

Merrill Meadow | Whitehead Institute • mit
April 19, 2022 ~9 min


New computational tool predicts cell fates and genetic perturbations

The technique can help predict a cell’s path over time, such as what type of cell it will become.

Greta Friar | Whitehead Institute • mit
Feb. 3, 2022 ~9 min

An on-off switch for gene editing

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.

Eva Frederick | Whitehead Institute • mit
April 14, 2021 ~9 min

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