In clinical study, blood test can detect range of cancers

In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy.

Harvard Gazette • harvard
March 31, 2020 ~4 min

Tags:  dna  cancer  basic-research  harvard-medical-school  health-medicine  annals-of-oncology  grail  pathfinder

How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy • harvard
Feb. 14, 2020 ~7 min

Tags:  science-technology  dna  chemistry  crispr  genome  chemistry-and-chemical-biology  rna  gene-editing  broad-institute  caitlin-mcdermott-murphy  cas9  base-editing  base-editors  biotechnology-nature  david-liu  genetic-disease  genetic-engineering  sickle-cell-anemia

Study likens Earth’s evolution to creation of Frankenstein’s monster

The evolution of the first building blocks on Earth may have been messier than previously thought, likening it to the mishmash creation of Frankenstein’s monster.

Caitlin McDermott-Murphy • harvard
Jan. 28, 2020 ~4 min

Tags:  science-technology  engineering  dna  chemistry  genetics  basic-research  chemistry-and-chemical-biology  jack-szostak  origins-of-life  rna  science  caitlin-mcdermott-murphy  primordial-soup  prebiotic  seohyun-kim

Evolution more complex than ‘survival of the fittest’ had us believe

By re-barcoding the DNA of yeast, researchers were able to follow evolution for approximately 1,000 generations, finding surprises along the way.

Clea Simon • harvard
Nov. 13, 2019 ~4 min

Tags:  science-technology  dna  evolution  physics  yeast  organismic-and-evolutionary-biology  alex-n-nguyen-ba  barcoding  ivana-cvijovic  michael-desai

Harvard researchers create DNA ‘propellers’

Understanding how DNA and proteins interact — or fail to — could help answer fundamental biological questions about human health and disease.

Caitlin McDermott-Murphy • harvard
July 19, 2019 ~7 min

Tags:  science-technology  dna  chemistry  biotechnology  optics  nanotechnology  nature  microscopy  biomechanics  cell-biology  micromachines  molecular-biology  xiaowei-zhuang

New tool calculates genetic risk for obesity

A “polygenic score” for obesity, a quantitative tool that predicts an individual’s inherited risk for becoming overweight, may identify an opportunity for early intervention.

Karen Zusi • harvard
April 18, 2019 ~6 min

Tags:  dna  obesity  genetic  health-medicine  uk-biobank  broad-institute  amit-v-khera  avon-longitudinal-study-of-parents-and-children  clinical-interventions  coronary-artery-risk-development-in-young-adults-study  framingham-offspring-study  polygenic-score  polygenic-scoring

Harvard study unlocks a key to regeneration

Led by Assistant Professor of Organismic and Evolutionary Biology Mansi Srivastava, a team of researchers is shedding new light on how animals perform whole-body regeneration, and uncovering a number of DNA switches that appear to control genes used in the process.

Peter Reuell • harvard
March 14, 2019 ~9 min

Tags:  science-technology  dna  genes  faculty-of-arts-and-sciences  fas  harvard  peter-reuell  reuell  andrew-gehrke  early-growth-response  egr  gehrke  mansi-srivastava  noncoding-dna  regeneration  srivastava  three-banded-panther-worms  whole-body-regeneration  worms

Science writers discuss ‘sideways’ DNA at Harvard

Science authors David Quammen and Carl Zimmer both have recent books showing that DNA is not only passed down from our ancestors but can also come from viruses, siblings, and even our children.

Clea Simon • harvard
March 1, 2019 ~5 min

Tags:  science-technology  dna  carl-woese  carl-zimmer  david-quammen  evolution-matters

Science writers discuss ‘sideways’ DNA at Harvard

Science authors David Quammen and Carl Zimmer both have recent books showing that DNA is not only passed down from our ancestors but can also come from viruses, siblings, and even our children.

Clea Simon • harvard
March 1, 2019 ~5 min

Tags:  science-technology  dna  carl-woese  carl-zimmer  david-quammen  evolution-matters

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