Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.

K. Lisa Yang Brain-Body Center to investigate the brain’s complex relationship with other body systems.

Family trees of lung cancer cells reveal how cancer evolves from its earliest stages to an aggressive form capable of spreading throughout the body.

Researchers find RNA-guided enzymes are more diverse and widespread than previously believed.

Made of components found in the human body, the programmable system is a step toward safer, targeted delivery of gene editing and other molecular therapeutics.

Novel method, developed by McGovern Institute researchers, may lead to safer, more efficient gene therapies.

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.

Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.