Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps

Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 22, 2024 ~9 min

A protein found in human sweat may protect against Lyme disease

Researchers also found that a variant of the protein is not as protective against the bacteria and increases susceptibility to the disease.

Anne Trafton | MIT News • mit
March 19, 2024 ~8 min


How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice

Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 7, 2024 ~8 min

Deciphering the cellular mechanisms behind ALS

Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.

Michaela Jarvis | School of Engineering • mit
March 6, 2024 ~8 min

A noninvasive treatment for “chemo brain”

Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.

Anne Trafton | MIT News • mit
March 6, 2024 ~7 min

A new test could predict how heart attack patients will respond to mechanical pumps

Performing this test could help doctors prevent dysfunction that can occur when the right and left ventricles of the heart become imbalanced.

Anne Trafton | MIT News • mit
Feb. 14, 2024 ~7 min

A new drug candidate can shrink kidney cysts

A compound originally developed to treat cancer could be repurposed to treat polycystic kidney disease, an inherited condition that can lead to kidney failure.

Anne Trafton | MIT News • mit
Jan. 22, 2024 ~7 min

Nanoparticle-delivered RNA reduces neuroinflammation in lab tests

MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.

David Orenstein | Picower Institute • mit
Dec. 15, 2023 ~7 min


3 Questions: Darrell Irvine on making HIV vaccines more powerful

Human volunteers will soon begin receiving an HIV vaccine that contains an adjuvant developed in Irvine’s lab, which helps to boost B cell responses to the vaccine.

Anne Trafton | MIT News • mit
Dec. 12, 2023 ~5 min

Smart pill can track key biological markers in real-time

Coupling engineered bacteria with low-power electronics could be highly effective in diagnosis, treatment of bowel diseases.

Elizabeth A. Thomson | Materials Research Laboratory • mit
Sept. 8, 2023 ~8 min

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