In a study of cells from nearly 400 ALS patients, researchers identified genomic regions with chemical modifications linked to disease progression.

Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

Researchers also found that a variant of the protein is not as protective against the bacteria and increases susceptibility to the disease.

Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.

Professor Ernest Fraenkel has decoded fundamental aspects of Huntington’s disease and glioblastoma, and is now using computation to better understand amyotrophic lateral sclerosis.

Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.

Performing this test could help doctors prevent dysfunction that can occur when the right and left ventricles of the heart become imbalanced.

A compound originally developed to treat cancer could be repurposed to treat polycystic kidney disease, an inherited condition that can lead to kidney failure.

MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.

Human volunteers will soon begin receiving an HIV vaccine that contains an adjuvant developed in Irvine’s lab, which helps to boost B cell responses to the vaccine.