A causal theory for studying the cause-and-effect relationships of genes

By sidestepping the need for costly interventions, a new method could potentially reveal gene regulatory programs, paving the way for targeted treatments.

Adam Zewe | MIT News • mit
Nov. 7, 2024 ~7 min

Study across multiple brain regions discerns Alzheimer’s vulnerability and resilience factors

Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition.

David Orenstein | The Picower Institute for Learning and Memory • mit
July 24, 2024 ~11 min


CHARMed collaboration creates a potent therapy candidate for fatal prion diseases

A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.

Greta Friar | Whitehead Institute • mit
June 27, 2024 ~12 min

Scientists preserve DNA in an amber-like polymer

With their “T-REX” method, DNA embedded in the polymer could be used for long-term storage of genomes or digital data such as photos and music.

Anne Trafton | MIT News • mit
June 13, 2024 ~7 min

New technique reveals how gene transcription is coordinated in cells

By capturing short-lived RNA molecules, scientists can map relationships between genes and the regulatory elements that control them.

Anne Trafton | MIT News • mit
June 5, 2024 ~8 min

Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps

Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 22, 2024 ~9 min

A protein found in human sweat may protect against Lyme disease

Researchers also found that a variant of the protein is not as protective against the bacteria and increases susceptibility to the disease.

Anne Trafton | MIT News • mit
March 19, 2024 ~8 min

Scientists develop a rapid gene-editing screen to find effects of cancer mutations

With the new technique, MIT researchers hope to identify mutations that could be targeted with new cancer therapies.

Anne Trafton | MIT News • mit
March 12, 2024 ~9 min


How early-stage cancer cells hide from the immune system

A new study finds precancerous colon cells turn on a gene called SOX17, which helps them evade detection and develop into more advanced tumors.

Anne Trafton | MIT News • mit
Feb. 28, 2024 ~6 min

Noninvasive technique reveals how cells’ gene expression changes over time

MIT researchers can now track a cell’s RNA expression to investigate long-term processes like cancer progression or embryonic development.

Anne Trafton | MIT News • mit
Jan. 10, 2024 ~7 min

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