How cell identity is preserved when cells divide

MIT study suggests 3D folding of the genome is key to cells’ ability to store and pass on “memories” of which genes they should express.

Anne Trafton | MIT News • mit
Nov. 16, 2023 ~9 min

Making genetic prediction models more inclusive

MIT computer scientists developed a way to calculate polygenic scores that makes them more accurate for people across diverse ancestries.

Anne Trafton | MIT News • mit
Oct. 26, 2023 ~9 min


Thousands of programmable DNA-cutters found in algae, snails, and other organisms

New research finds RNA-guided enzymes called Fanzors are widespread among eukaryotic organisms.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Oct. 13, 2023 ~6 min

A more effective experimental design for engineering a cell into a new state

By focusing on causal relationships in genome regulation, a new AI method could help scientists identify new immunotherapy techniques or regenerative therapies.

Adam Zewe | MIT News • mit
Oct. 2, 2023 ~8 min

Decoding the complexity of Alzheimer’s disease

By analyzing epigenomic and gene expression changes that occur in Alzheimer’s disease, researchers identify cellular pathways that could become new drug targets.

Anne Trafton | MIT News • mit
Sept. 28, 2023 ~12 min

Study explains why certain immunotherapies don’t always work as predicted

The findings could help doctors identify cancer patients who would benefit the most from drugs called checkpoint blockade inhibitors.

Anne Trafton | MIT News • mit
Sept. 14, 2023 ~8 min

Study connects neural gene expression differences to functional distinctions

Researchers compared a pair of superficially similar motor neurons in fruit flies to examine how their differing use of the same genome produced distinctions in form and function.

David Orenstein | The Picower Institute for Learning and Memory • mit
Aug. 25, 2023 ~8 min

It takes three to tango: transcription factors bind DNA, protein, and RNA

Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.

Greta Friar | Whitehead Institute • mit
July 17, 2023 ~7 min


Focus on function helps identify the changes that made us human

A new approach for identifying significant differences in gene use between closely-related species provides insights into human evolution.

Greta Friar | Whitehead Institute • mit
July 6, 2023 ~11 min

Researchers uncover a new CRISPR-like system in animals that can edit the human genome

The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.

Leah Eisenstadt | McGovern Institute for Brain Research | Broad Institute • mit
June 28, 2023 ~7 min

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