Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.

Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.