Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
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By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.
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Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
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CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.
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Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.
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With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.
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Department of Biology kicks off IAP seminar series with a lecture by synthetic-biology visionary George Church.
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“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.
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MIT associate professor and member of the Broad Institute and McGovern Institute recognized for commitment to invention, collaboration, and mentorship.
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Five recipients honored for their fundamental and complementary accomplishments related to CRISPR-Cas9.
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