Alzheimer’s risk gene undermines insulation of brain’s “wiring”
In people carrying APOE4, a key brain cell mismanages cholesterol needed to insulate neurons properly — another sign APOE4 contributes to disease by disrupting brain lipids.
Nov. 22, 2022 • ~8 min
Celebrating 20 years of discovery, Picower Institute looks ahead to continuing impact
At an exhibition marking two decades since a transformative gift from the Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond.
Oct. 12, 2022 • ~15 min
When Alzheimer’s degrades cells that cross hemispheres, visual memory suffers
Research reveals cells that span brain hemispheres to coordinate activity in visual processing centers, shows Alzheimer’s degrades their structure and function.
Aug. 24, 2022 • ~7 min
New findings reveal how neurons build and maintain their capacity to communicate
Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections.
July 21, 2022 • ~8 min
A single memory is stored across many connected brain regions
Innovative brain-wide mapping study shows that an “engram,” the ensemble of neurons encoding a memory, is widely distributed and includes regions not previously realized.
May 2, 2022 • ~9 min
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