Novel approach reverses amblyopia in animals

By temporarily suspending retinal activity in the non-amblyopic eye of animal models, neuroscientists restrengthen the visual response in the "lazy" eye, even at ages after the critical period when patch therapy fails.

David Orenstein | Picower Institute for Learning and Memory • mit
Sept. 20, 2021 ~6 min

A pivot from accounting to neuroscience

Through a summer research program at MIT, Patricia Pujols explored the neuromuscular junction, and a future in science.

Alison Gold | School of Science • mit
Aug. 26, 2021 ~8 min


Brain’s “memory center” is needed to recognize image sequences, but not single sights

The visual cortex stores and remembers individual images, but mice can’t recognize image sequences without guidance from the hippocampus.

David Orenstein | Picower Institute for Learning and Memory • mit
July 26, 2021 ~7 min

Memory-making involves extensive DNA breaking

To quickly express learning and memory genes, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows.

David Orenstein | Picower Institute for Learning and Memory • mit
July 14, 2021 ~7 min

As novel sights become familiar, different brain rhythms and neurons take over

As “visual recognition memory” emerges in the visual cortex, one circuit of inhibitory neurons supplants another, and slower neural oscillations prevail.

David Orenstein | Picower Institute for Learning and Memory • mit
June 24, 2021 ~6 min

New algorithms show accuracy, reliability in gauging unconsciousness under general anesthesia

Machine learning software advances could help anesthesiologists optimize drug dose.

David Orenstein | Picower Institute for Learning and Memory • mit
May 26, 2021 ~8 min

Anesthesia doesn't simply turn off the brain — it changes its rhythms

Simultaneous measurement of neural rhythms and spikes across five brain areas reveals how propofol induces unconsciousness.

David Orenstein | Picower Institute for Learning and Memory • mit
May 11, 2021 ~6 min

Mice naturally engage in physical distancing, study finds

MIT neuroscientists have identified a brain circuit that stops mice from mating with others that appear to be sick.

Anne Trafton | MIT News Office • mit
March 31, 2021 ~6 min


Study offers an explanation for why the APOE4 gene enhances Alzheimer’s risk

The gene variant disrupts lipid metabolism, but in cell experiments the effects were reversed by choline supplements.

Anne Trafton | MIT News Office • mit
March 3, 2021 ~7 min

Basic cell health systems wear down in Huntington’s disease, analysis shows

A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.

David Orenstein | Picower Institute for Learning and Memory • mit
Feb. 24, 2021 ~6 min

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