New study reveals that living through the COVID-19 pandemic may trigger brain inflammation that contributes to fatigue, concentration difficulties, and depression.

The substantial antidepressant effects of psilocybin-assisted therapy, alongside supportive psychotherapy, may last at least a year for some patients.

A well-intentioned public health message has had serious negative impacts on the treatment of young people for depression.

Drug manufacturers often shun the use of placebos in clinical trials. But research suggests that placebos could play an important role in the treatment of depression, pain and other maladies.

In the first published survey of users of the hemp-derived compound, respondents highlight some important therapeutic effects.

People with moderate or greater symptoms of depression were more likely to believe at least 1 of 4 false statements about COVID-19 vaccines, research finds.

Sadness isn't surprising during the thick of winter and the third year of COVID-19. Here are five, science-backed ways to protect your mood.

Return to an old flame? Watch out. New findings link on-and-off romance, or relationship cycling, with anxiety and depression.

Parents with kids at home during the COVID-19 pandemic aren't doing any worse mentally than adults without kids. They may even be doing better.