How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice

Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 7, 2024 ~8 min

A noninvasive treatment for “chemo brain”

Stimulating gamma brain waves may protect cancer patients from memory impairment and other cognitive effects of chemotherapy.

Anne Trafton | MIT News • mit
March 6, 2024 ~7 min


Simons Center’s collaborative approach propels autism research, at MIT and beyond

Team-based targeted projects, multi-mentor fellowships ensure that scientists studying social cognition, behavior, and autism integrate multiple perspectives and approaches to pressing questions.

David Orenstein | Simons Center for the Social Brain • mit
Jan. 30, 2024 ~12 min

Evidence that gamma rhythm stimulation can treat neurological disorders is emerging

Researchers survey a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of noninvasive sensory, electrical, or magnetic stimulation of gamma brain rhythms.

David Orenstein | The Picower Institute for Learning and Memory • mit
Jan. 18, 2024 ~9 min

Study reveals a universal pattern of brain wave frequencies

Across mammalian species, brain waves are slower in deep cortical layers, while superficial layers generate faster rhythms.

Anne Trafton | MIT News • mit
Jan. 18, 2024 ~9 min

Nanoparticle-delivered RNA reduces neuroinflammation in lab tests

MIT researchers find that in mice and human cell cultures, lipid nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s.

David Orenstein | Picower Institute • mit
Dec. 15, 2023 ~7 min

How a mutation in microglia elevates Alzheimer’s risk

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation, and contribute to Alzheimer’s pathology in other ways.

David Orenstein | The Picower Institute for Learning and Memory • mit
Dec. 4, 2023 ~7 min

Elly Nedivi receives 2023 Kreig Cortical Kudos Discoverer Award

The neuroscientist is recognized for her ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience.

David Orenstein | The Picower Institute for Learning and Memory • mit
Nov. 29, 2023 ~3 min


Anesthesia technology precisely controls unconsciousness in animal tests

An advanced closed-loop anesthesia delivery system that monitors brain state to tailor propofol dose and achieve exactly the desired level of unconsciousness could reduce post-op side effects.

David Orenstein | The Picower Institute for Learning and Memory • mit
Nov. 7, 2023 ~8 min

Study advances understanding of visual recognition memory

Scientists have invested decades in piecing together how our vision is so good at recognizing what’s familiar. A new study overcomes an apparent discrepancy in data to reveal a new insight into how it works.

David Orenstein | The Picower Institute for Learning and Memory • mit
Oct. 11, 2023 ~7 min

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