Research advances technology of AI assistance for anesthesiologists

A new deep-learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general anesthesia could augment patient monitoring.

David Orenstein | Picower Institute for Learning and Memory • mit
Feb. 14, 2022 ~7 min

A new “atlas” of cells that carry blood to the brain

Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease.

Anne Trafton | MIT News Office • mit
Feb. 14, 2022 ~9 min


“Traveling” nature of brain waves may help working memory work

The act of holding information in mind is accompanied by coordination of rotating brain waves in the prefrontal cortex, a phenomenon that may convey specific advantages, a new study suggests.

David Orenstein | Picower Institute for Learning and Memory • mit
Feb. 10, 2022 ~7 min

In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

David Orenstein | Picower Institute • mit
Jan. 10, 2022 ~7 min

Research finds potential mechanism linking autism, intestinal inflammation

Infection during pregnancy with elevated levels of the cytokine IL-17a may yield microbiome alterations that prime offspring for aberrant immune responses, mouse study suggests.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 9, 2021 ~8 min

Study reveals a protein’s key contribution to heterogeneity of neurons

Tomosyn’s tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 7, 2021 ~7 min

Feast or forage? Study finds circuit that helps a brain decide

By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 6, 2021 ~7 min

Study links gene to cognitive resilience in the elderly

The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia.

Anne Trafton | MIT News Office • mit
Nov. 3, 2021 ~6 min


Study shows fragile X treatment can incur resistance, suggests ways around it

While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental-critical period.

David Orenstein | Picower Institute for Learning and Memory • mit
Oct. 15, 2021 ~10 min

Behind the scenes, brain circuit ensures vision remains reliable

A study of mice watching movies shows our brain cells rely on a circuit of inhibitory neurons to help ensure that the same images are represented consistently.

David Orenstein | Picower Institute for Learning and Memory • mit
Sept. 27, 2021 ~7 min

/

21