New test method to detect kidney cancers

A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists.

Richard Saltus • harvard
June 22, 2020 ~4 min

Tags: cancer health-medicine dana-farber-cancer-institute kidney-cancer biopsy

Dramatic drops in ER visits likely led to uncounted deaths

A Beth Israel Deaconess Medical Center study showed dramatic drops in hospital visits for heart attacks and stroke, which likely led to uncounted deaths at home during the COVID crisis. Perhaps more troubling is the potential for long-term damage to decades’ work to catch conditions in their earliest, most treatable stages.

Alvin Powell • harvard
May 22, 2020 ~12 min

Tags: stroke cancer covid-19 coronavirus harvard-medical-school health-medicine alvin-powell heart-attack beth-israel-deaconess-medical-center emergency-room dhruv-kazi

A connection between ancestry and the molecular makeup of cancer

A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.

Rob Levy • harvard
May 11, 2020 ~7 min

Tags: cancer basic-research health-medicine tumors broad-institute human-genome-project ancestry nci-cancer-genome-analysis-network

Scientists produce a reference map of human protein interactions

Scientists produce a reference map of human protein interactions, releasing data helpful for understanding diseases including cancer and infectious diseases such as COVID-19.

Jovana Drinjakovic • harvard
April 8, 2020 ~7 min

Tags:  science-technology  infectious-diseases  cancer  covid-19  genes  basic-research  dana-farber-cancer-institute  center-for-cancer-systems-biology  human-genome-project  human-reference-interactome  interactome

In clinical study, blood test can detect range of cancers

In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy.

Harvard Gazette • harvard
March 31, 2020 ~4 min

Tags:  dna  cancer  basic-research  harvard-medical-school  health-medicine  annals-of-oncology  grail  pathfinder

Removing the constraining requirements at gene editing site

Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.

Harvard Gazette • harvard
March 26, 2020 ~3 min

Tags:  science-technology  crispr  cancer  basic-research  mgh  blindness  gene-editing  benjamin-p-kleinstiver  cas9  center-for-genomic-medicine

U.S. life expectancy goes up as cancer deaths go down

A decline in cancer mortality was a prominent feature of recent good news about U.S. life expectancy. The Gazette spoke with the director of the Chan School’s Zhu Family Center for Global Cancer Prevention to understand why.

Alvin Powell • harvard
Feb. 21, 2020 ~14 min

Tags:  prostate-cancer  cancer  breast-cancer  basic-research  health-medicine  alvin-powell  harvard-th-chan-school-of-public-health  timothy-rebbeck  zhu-family-center-for-global-cancer-prevention  life-expectancy  cervical-cancer  disparities  melanoma  national-center-for-health-statistic

New class of enzymes could lead to bespoke diets, therapeutics

Professor Emily Balskus and her team have identified an entirely new class of enzymes that degrade chemicals essential for neurological health, but also help digest foods like nuts, berries, and tea, releasing nutrients that may impact human health.

Caitlin McDermott-Murphy • harvard
Feb. 18, 2020 ~6 min

Tags:  science-technology  chemistry  diet  cancer  bacteria  parkinsons-disease  basic-research  emily-balskus  chemistry-and-chemical-biology  science  caitlin-mcdermott-murphy  microbiome  vayu-maini-rekdal  microbes  berries  bespoke-diets  chocolate  coffee  dopamine  enzymes  gut  l-dopa  microbiology  nutrition  nuts

Better delivery system for sending chemo to cancerous lung tissue

A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

Lindsay Brownell • harvard
Nov. 13, 2019 ~8 min

Tags:  science-technology  engineering  cancer  basic-research  chemotherapy  john-a-paulson-school-of-engineering-and-applied-sciences  wyss-institute-for-biologically-inspired-engineering  lung-cancer  biodegradable-polymer  elect  erythrocyte-leveraged-chemotherapy  trojan-horse

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