Study: Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps

Single-cell gene expression patterns in the brain, and evidence from follow-up experiments, reveal many shared cellular and molecular similarities that could be targeted for potential treatment.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 22, 2024 ~9 min

A protein found in human sweat may protect against Lyme disease

Researchers also found that a variant of the protein is not as protective against the bacteria and increases susceptibility to the disease.

Anne Trafton | MIT News • mit
March 19, 2024 ~8 min


Scientists develop a rapid gene-editing screen to find effects of cancer mutations

With the new technique, MIT researchers hope to identify mutations that could be targeted with new cancer therapies.

Anne Trafton | MIT News • mit
March 12, 2024 ~9 min

How early-stage cancer cells hide from the immune system

A new study finds precancerous colon cells turn on a gene called SOX17, which helps them evade detection and develop into more advanced tumors.

Anne Trafton | MIT News • mit
Feb. 28, 2024 ~6 min

Noninvasive technique reveals how cells’ gene expression changes over time

MIT researchers can now track a cell’s RNA expression to investigate long-term processes like cancer progression or embryonic development.

Anne Trafton | MIT News • mit
Jan. 10, 2024 ~7 min

How cell identity is preserved when cells divide

MIT study suggests 3D folding of the genome is key to cells’ ability to store and pass on “memories” of which genes they should express.

Anne Trafton | MIT News • mit
Nov. 16, 2023 ~9 min

Making genetic prediction models more inclusive

MIT computer scientists developed a way to calculate polygenic scores that makes them more accurate for people across diverse ancestries.

Anne Trafton | MIT News • mit
Oct. 26, 2023 ~9 min

Thousands of programmable DNA-cutters found in algae, snails, and other organisms

New research finds RNA-guided enzymes called Fanzors are widespread among eukaryotic organisms.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Oct. 13, 2023 ~6 min


A more effective experimental design for engineering a cell into a new state

By focusing on causal relationships in genome regulation, a new AI method could help scientists identify new immunotherapy techniques or regenerative therapies.

Adam Zewe | MIT News • mit
Oct. 2, 2023 ~8 min

Decoding the complexity of Alzheimer’s disease

By analyzing epigenomic and gene expression changes that occur in Alzheimer’s disease, researchers identify cellular pathways that could become new drug targets.

Anne Trafton | MIT News • mit
Sept. 28, 2023 ~12 min

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