How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice

Study finds stimulating a key brain rhythm with light and sound increases peptide release from interneurons, driving clearance of an Alzheimer’s protein.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 7, 2024 ~8 min

Study advances understanding of visual recognition memory

Scientists have invested decades in piecing together how our vision is so good at recognizing what’s familiar. A new study overcomes an apparent discrepancy in data to reveal a new insight into how it works.

David Orenstein | The Picower Institute for Learning and Memory • mit
Oct. 11, 2023 ~7 min


Canceling noise to improve quantum devices

MIT researchers develop a protocol to extend the life of quantum coherence.

Peter Reuell | Department of Nuclear Science and Engineering • mit
Sept. 6, 2023 ~11 min

Molecule reduces inflammation in Alzheimer’s models

A potential new Alzheimer’s drug represses the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons, and improving cognition in preclinical tests.

David Orenstein | The Picower Institute for Learning and Memory • mit
Sept. 5, 2023 ~8 min

Brain networks encoding memory come together via electric fields, study finds

Electric fields shared among neurons via “ephaptic coupling” provide the coordination necessary to assemble the engrams that represent remembered information.

David Orenstein | The Picower Institute for Learning and Memory • mit
July 24, 2023 ~8 min

Atlas of human brain blood vessels highlights changes in Alzheimer’s disease

MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.

Rachel Gordon | MIT CSAIL • mit
June 21, 2023 ~17 min

40 Hz vibrations reduce Alzheimer’s pathology, symptoms in mouse models

Tactile stimulation improved motor performance, reduced phosphorylated tau, preserved neurons and synapses, and reduced DNA damage, a new study shows.

David Orenstein | The Picower Institute for Learning and Memory • mit
June 5, 2023 ~7 min

That moment when you’re nodding off is a sweet spot for creativity

A new study finds people are more creative after waking from the earliest stage of sleep, especially when they are guided to dream about a particular topic.

Anne Trafton | MIT News Office • mit
May 15, 2023 ~10 min


New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.

David Orenstein | Picower Institute for Learning and Memory • mit
Jan. 18, 2023 ~6 min

Holding information in mind may mean storing it among synapses

Comparing models of working memory with real-world data, MIT researchers find information resides not in persistent neural activity, but in the pattern of its connections.

David Orenstein | Picower Institute for Learning and Memory • mit
Jan. 12, 2023 ~8 min

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